Ebastine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 13.10.2021

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Definition
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Indication
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Symptomatic treatment of seasonal and perennial allergic rhinitis with or without allergic conjunctivitis, itching, to reduce the formation of new wheals in urticaria.

Pregnancy/nursing period
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Should not be used during pregnancy (insufficient data available). Contraindicated during lactation (do not use, because due to insufficient data it is not known whether the active substance passes into breast milk).

Dosage and method of use
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  • Allergic rhinitis: children > 12 years and adults: 1 x/day 10 mg p.o. In case of severe symptoms and perennial allergic rhinitis, increase the dose to 20 mg p.o. once/day.
  • Urticaria: adults, adolescents > 18 years: once/day 10 mg p.o.

Undesirable effects
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Occasionally or rarely headaches, fatigue, dry mouth, pharyngitis, abdominal pain, indigestion, weakness, nosebleeds, rhinitis, sinusitis, nausea, insomnia, etc.

Interactions
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Ketoconazole or erythromycin: higher ebastine plasma levels and an increase of the QTc interval of about 10 msec longer than after the sole administration of ketoconazole or erythromycin.

Contraindication
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Severe liver or kidney failure.

Notice!

Do not use on children or patients under 18 years of age (insufficient data available)!

Preparations
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Ebastel® 10 mg film-coated tablets, Ebastel® 20 mg film-coated tablets

Outgoing links (1)

Antihistamines;

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Last updated on: 13.10.2021