Cytomegalovirus ulcer B25.9
Synonym(s)
Cytomegaly ulcus
Definition
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Torpidal, ulcerous, local cytomegalovirus infection (see below cytomegaly), which occurs in immunocompromised patients.
Etiopathogenesis
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CMV infection, the origin is unclear; both disseminated and local infections are discussed.
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Localization
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Mainly on the genital region, perianal region, also orally (Drozd B et al. 2019); rarely on the lower extremities.
Clinic
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Large (2.0-20 cm in diameter) and deep-reaching, sharply defined, painful ulcer penetrating the subcutis and muscles in immunocompromised patients (especially those infected with HIV).
Differential diagnosis
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Bacterial ulcers
Fournier gangrene(Gangraena acuta genitalium)
Internal therapy
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Successes have been described with the preparation Valganciclovir, also with Foscarnet and Ganciclovir.
Literature
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- Class U et al (2008) Skin infections in organ transplant patients. JDDG 6: 98-105Drozd
B et al (2019) Cutaneouscytomegalovirus
manifestations, diagnosis, and treatment: a review. DermatolOnline
J 25:13030/qt84f936cp. - Lambert EM et al (2004) Cytomegalovirus ulcer. Arch Dermatol 140: 1199-2101
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Incoming links (1)
Anal fissure;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer
