Cetirizine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Allergic reactions, eczema, pruritus, allergic rhinitis, urticaria.

Limited indication
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Second and third trimester pregnancies.

Dosage and method of use
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  • Adults/children > 12 years: once/day 10 mg p.o.
  • Children 2-12 years: 1 time per day 5 mg p.o. or 1 time per day 10 trp. p.o.

Undesirable effects
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Allergic reactions, paragroup allergy (juice, trp.), dry mouth, headache, gastrointestinal disorders, fatigue, dizziness, gastrointestinal disorders, transaminase increase.

Contraindication
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Pregnancy 1st trimester, lactation, children < 2 years, severe kidney disease, paragroup allergy (juice, drops).

Preparations
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Cetirizine Solution 1A Pharma, Zyrtec, Reactine, Cetirizine-Ratiopharm, Cetirizine Hexal; Zyrtec Duo (combination preparation with pseudoephedrine)

Note(s)
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Consists of 50% levocetirizine and 50% ineffective dextrocetirizine (dextrocetirizine has no antihistaminergic effect).

Literature
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  1. Ambros-Rudolph CM (2006) Dermatoses of pregnancy. J Dtsch Dermatol Ges 4: 748-759
  2. del Cuvillo A et al (2006) Comparative pharmacology of the H1 antihistamines. J Investig Allergol Clin Immunol 16: 3-12

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Last updated on: 29.10.2020