Cd7

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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markers for: T cells, NK cells, monocytes, pre-B cells

Structure: Transmembrane protein (40 kDa)

Note: CD7 (gp40), belonging to the immunoglobulin superfamily, is also expressed in acute lymphocytic leukemia (T-cell ALL). Very early T-cell antigen. The marker combination CD3+CD4+CD7- is pathognomic for Sézary cells in peripheral blood.

Application: FACS, IHC (G), IF

Literature
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  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.

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Last updated on: 29.10.2020