Synonym(s)
Cluster of Differentiation 280; Macrophage mannose receptor 2; Mannose receptor; MRC2
DefinitionThis section has been translated automatically.
Acronym for Cluster of differentiation (CD) 280, the mannose receptor (CD280) is a C-type lectin primarily expressed by macrophages and immature dendritic cells. CD280 is a transmembrane receptor protein encoded by the MRC2 receptor located on chromosome 17q23. The receptor protein has an extracellular N-terminus and an intracellular C-terminus. CD 280 is primarily synthesized as an inactive precursor, but upon activation it is proteolytically cleaved into its active form. This process takes place in the Golgi apparatus.
For further information see CD206
Prof. Dr. med. Peter Altmeyer