Calcinosis, tumour-like L94.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

hip stone; tumoral calcinosis

History
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Duret, 1899; Inclan, 1943

Definition
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Almost exclusively in Africa occurring Calcinosis cutis with slowly growing, cutaneously-subcutaneously located calcified nodes, especially in the area of the large joints. Partly attributed to Calcinosis idiopathica, partly to Calcinosis dystrophica.

Etiopathogenesis
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Unexplained, metabolic disorder mostly not detectable (in some cases an elevated serum phosphate level was found).

Manifestation
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Especially among black Africans, very rarely among whites. Usually begins in childhood or early adulthood. Family clustering.

Localization
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Proximity of the large joints (without direct joint involvement): hip, elbow, shoulder joint.

Clinical features
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One or more subcutaneously located, easily movable, up to 5 cm thick, hard, non-pressure dolent nodes. Possibly reddening of the overlying skin. Years of slow growth. Possibly ulceration and breakthrough to the outside.

Histology
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Initially destruction of collagen fibres, cyst formation, foreign body reaction; later extensive calcification zones.

Diagnosis
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X-ray, histology, sonography.

Differential diagnosis
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Therapy
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Surgical removal if necessary. See also Calcinosis idiopathica; see also Calcinosis dystrophica.

Note(s)
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The synonym "Hip Stone" comes from the name of the disease in New Guinea.

Literature
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  1. Abraham Z et al (1996) Tumoral calcinosis: report of a case and brief review of the literature. J Dermatol 23: 545-550
  2. Arikawa J et al (2000) Tumoral calcinosis: a case report with an electron microscopic study. Eur J Dermatol 10: 52-54
  3. Bittmann S et al (2003) Tumoral calcinosis of the gluteal region in a child: case report with overview of different soft-tissue calcifications. J Pediatrics Surgery 38: E4-7
  4. Duret MH (1899) Tumeurs multiples et singulieres des bourses sereuses (endotheliomes peut-etre d'origine parasitaire). Bull Mem Soc Anat Paris 74: 725-731
  5. Inclan A et al (1943) Tumoral calcinosis. JAMA 121: 490-495
  6. McKee PH et al (1982) Tumoral Calcinosis: A Pathological Study of 56 Cases. Br J Dermatol 107: 669-674
  7. Zimmermann J et al (1990) Tumor-like calcinosis. Dermatologist 41: 475-377

Incoming links (2)

Hip stone; Tumoral calcinosis;

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Last updated on: 29.10.2020