DefinitionThis section has been translated automatically.
Anticholinergic (bornaprin hydrochloride).
Pharmacodynamics (Effect)This section has been translated automatically.
Blockade of the acetylcholine receptors; compensation of the disturbed acetylcholine - dopamine balance.
You might also be interested in
IndicationThis section has been translated automatically.
Hyperhidrosis (Sergi R et al. 2008); Parkinson's syndromes (Cantello R et al. 1986).
Pregnancy/nursing periodThis section has been translated automatically.
Do not use during pregnancy (insufficient data available). Do not use when breastfeeding (anticholinergics inhibit lactation).
Dosage and method of useThis section has been translated automatically.
Hyperhidrosis: Initial 1mal/day 1/2 p.o. (2 mg bornaprine hydrochloride). Maintenance dose: 1-2 tbl/day (4-8 mg boron aprine hydrochloride). The prescribed daily dose should be divided into 2-3 individual doses. Consumption during a meal.
Undesirable effectsThis section has been translated automatically.
Especially at higher doses: tiredness, dizziness and light-headedness, restlessness, agitation, confusion, occasional memory disorders, hallucinations, nervousness, headaches, sleep disorders, dry mouth.
PreparationsThis section has been translated automatically.
Sormodren®
Note(s)This section has been translated automatically.
Even when used as directed, the ability to react, actively participate in road traffic, operate machinery, etc. may be impaired. The preparation no longer plays a significant therapeutic role in hyperhidrosis or Parkinson's disease.
Note! Antidote: Acetylcholinesterase inhibitors, e.g. Physiostigmine.
LiteratureThis section has been translated automatically.
- Cantello R et al. (1986) Bornaprine vs placebo in Parkinson disease: double-blind controlled cross-over trial in 30 patients. Ital J Neurol Sci 7:139-143.
- Sergi R et al. (2008) Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients. Spinal Cord 46:571-573.
Prof. Dr. med. Peter Altmeyer