Aztreonam

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Antibiotic belonging to the group of monobactams.

Half-life
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1,5–2 h

Spectrum of action
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E. coli, Enterobacter spp., Haemophilus influenzae, Klebsiella spp., Moraganella morganii, Neisseria spp., Proteus spp., Providentia spp., Pseudomonas spp.

Indication
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Infections caused by Gram-negative pathogens in the area of the abdomen, respiratory and urinary tract, bones, joints, soft tissues, skin; meningitis, gonorrhoea.

Limited indication
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Pregnancy, nursing, newborns.

Dosage and method of use
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Adults: 3-8 g/day i.v. or i.m. in 3-4 ED Children: 45-120 mg/kg bw/day.

Undesirable effects
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Blood formation disorders, gastrointestinal disorders, allergic reactions, RR drop, headaches, dizziness, paraesthesias.

Notice! Cross allergy to penicillins and cephalosporins!

Interactions
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Do not mix with sodium hydrogen carbonate containing solutions!

Contraindication
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Hypersensitivity to monobactams, infections with gram-positive pathogens.

Preparations
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Azactam®

Incoming links (2)

Aztreonam; Monobactams;

Outgoing links (2)

Antibiotics; Monobactams;

Authors

Last updated on: 29.10.2020