HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Group of inflammatory diseases that are non-infectious, non-allergic, non-autoimmune in nature. The term "autoinflammatory diseases" includes hereditary diseases (e.g. hereditary periodic fever syndromes) induced by mutations of pattern-recognition receptors (PRRs) and disturbances of cytokine generation and balance (see immunodeficiencies primary/autoinflammatory diseases) but also non-hereditary acquired autoinflammatory diseases.
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ClassificationThis section has been translated automatically.
- Hereditary periodic fever syndromes, which are classified as primary immunodeficiencies/autoinflammatory diseases in the IUIS classification (2019)
- other hereditary and non-hereditary idiopathic fever syndromes, which are also grouped under the term "autoinflammatory syndromes":
- Still syndrome
- Adult onset Still's syndrome (AOSD)
- Schnitzler syndrome (urticarial exanthema)
- SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis)
- PASH syndrome (pyoderma gangraenosum, acne, suppurative hidradenitis)
- PAPA syndrome (pyoderma gangraenosum, acne, pyogenic arthritis)
- Proteasome-associated autoinflammatory syndrome 2 (PRAAS2)
Note(s)This section has been translated automatically.
Initially, the term "autoinflammatory syndromes" was coined for a small group of familial fever syndromes(see below Fever syndromes, hereditary, periodic; see below. Immunodeficiency primary (autoinflammatory diseases). This term has since been expanded to include an increasing number of acquired disorders. In 2010, a drug-induced autoinflammatory syndrome was described, the "autoinflammatory syndrome induced by adjuvants (ASIA)." The "Gulf War Syndrome" also belongs to this acquired group of diseases.
LiteratureThis section has been translated automatically.
- Braun-Falco M et al (2011) Skin involvement in autoinflammatory syndromes. SDDG 9: 232 - 245
- Israeli E (2012) Gulf War syndrome as a part of the autoimmune (autoinflammatory) syndrome induced by adjuvant (ASIA). Lupus 21:190-194.
Incoming links (6)Breastfeeding syndrome; Breastfeeding syndrome adultes; Papa syndrome; Sapho syndrome; Spondyloenchondrodysplasia; Sting-associated vasculopathy;
Outgoing links (11)Adverse drug reactions of the skin; Aefi; Breastfeeding syndrome; Breastfeeding syndrome adultes; Fever syndromes, hereditary, periodic (overview); Papa syndrome; Pash syndrome; PID autoinflammatory diseases ; Proteasome-associated autoinflammatory syndrome 2; Sapho syndrome; ... Show all
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