HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Autosomal-dominantly inherited, distinct skeletal dysplasia with premature ossification of the cranial sutures with midface hypoplasia, hypertelorism, tooth anomalies, cleft palate and syndactyly of fingers and toes.
Furthermore puberty precox and acne of varying degrees.
In very rare cases the acne efflorescences in this syndrome are arranged in stripes. This epidermal nevus called acne nevus type Munro is based on a postzygotic FGFR2 mutation.
EtiopathogenesisThis section has been translated automatically.
mutations of the fibroblast growth factor receptor -2 (FGFR2).
TherapyThis section has been translated automatically.
Incoming links (5)Acneneevus type munro; Acrocephalosyndactyly; Ebstein anomaly; Epidermal nevus organoid; Syndicate;
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.