DefinitionThis section has been translated automatically.
Oral contraceptives with antiandrogenic activity, e.g. consisting of ethinyl estradiol and cyproterone acetate.
IndicationThis section has been translated automatically.
Hormonal contraception, androgen-dependent diseases in women, such as acne papulopustulosa, acne conglobata, seborrhea, milder forms of hirsutism, alopecia androgenetica (see alopecia androgenetica in women, alopecia androgenetica in men).
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Limited indicationThis section has been translated automatically.
- Breastfeeding, discontinue 6 weeks before planned operations, long-term immobilization (e.g. after accidents), smokers > 30 years, liver diseases (e.g. porphyria), Z.n. thrombophlebitis.
- Monitoring in diabetes mellitus, hypertension, varicosis, phlebitis, otosclerosis, multiple sclerosis, epilepsy, minor chorea, latent tetany; women > 40 years.
Dosage and method of useThis section has been translated automatically.
From 5th to 26th cycle day 1 Drg./day p.o.
Undesirable effectsThis section has been translated automatically.
visual and hearing disorders, weight gain, chest tensions, changes in libido, thrombosis, gastrointestinal problems, liver tumours, chloasma, blood pressure increase, dizziness, headaches, depression.
InteractionsThis section has been translated automatically.
See Table 1.
ContraindicationThis section has been translated automatically.
Pregnancy, idiopathic icterus or severe pruritus (in the medical history), severe liver dysfunction, Dubin-Johnson or Rotor syndrome, previous or existing liver tumours, lipid metabolism disorders, Z. n. thrombosis or embolism, Z.n. apoplexy, Z.n. myocardial infarction, tendency to thrombosis, sickle cell anaemia, pemphigoid gestationis (in the medical history), worsening of otosclerosis in pregnancy, severe diabetes mellitus, migraine, severe forms of hypertension, breast or endometrial carcinoma.
PreparationsThis section has been translated automatically.
Diane 35, Climen
TablesThis section has been translated automatically.
Essential interactions of antiandrogen-estrogen combinations
Antidiabetics, oral |
Carbohydrate Tolerance ↓ |
Barbiturates |
contraceptive effect ↓ |
Broad spectrum antibiotics |
contraceptive effect ↓ |
Carbamazepine |
contraceptive effect ↓ |
Phenytoin |
contraceptive effect ↓ |
Rifampicin |
contraceptive effect ↓ |