DefinitionThis section has been translated automatically.
Albinism is the genetic absence of pigment. Clinically, it is a group of genetically different diseases characterized by a generalized or partial hypomelanosis of the skin, hair and eyes (oculocutaneous albinism - OCA) or of the eyes only (ocular albinism). (Note: only albinimus type IA and generalized vitiligo show a complete loss of pimples). The underlying cause is a congenital, mostly autosomal recessive inherited disorder of melanin synthesis with normal intraepidermal melanocyte count.
ClassificationThis section has been translated automatically.
The following entities can be distinguished:
- Oculocutaneous albinism (OCA types 1-7)
- Ocular albinism (dermatologically not relevant): 5 forms with varying degrees of iris depigmentation. Additionally photophobia, possibly nystagmus, strabismus, hypoplasia of the fovea centralis.
- Other, rare, syndromatic forms of albinism (also "albinoidism") with generalized, pronounced hypopigmentation and additional organ manifestations that are crucial for morbidity and prognosis:
You might also be interested in
General therapyThis section has been translated automatically.
External therapyThis section has been translated automatically.
Internal therapyThis section has been translated automatically.
Note(s)This section has been translated automatically.
LiteratureThis section has been translated automatically.
- Böhm M (2015) Differential diagnosis of hypomelanosis. dermatologist 66: 945-958
Incoming links (21)Achromia; Albinism; Albinism, oculocutaneous, brown; Albinism oculocutaneous tyrosinase-negative; Albinism oculocutaneous tyrosinase-positive; Albinism, oculocutaneous, yellow mutant; Albinism totalis; Albinism, universally complete; Albinoidism, oculocutaneous; Alphoderma; ... Show all
Outgoing links (12)Albinism oculocutaneous (overview); Beta-carotene; Camouflage; Chediak higashi syndrome; Cross syndrome; Griscelli syndrome; Hermansky-pudlak syndrome; Hypomelanosis; Light protection; Melanocyte; ... Show all
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.