HistoryThis section has been translated automatically.
Fetsch et al. 2001
DefinitionThis section has been translated automatically.
Rare, fibroblastically differentiated, myxoidal tumor of the skin which occurs mainly in the digital acra, here preferably periungual (more rarely subungual).
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Occurrence/EpidemiologyThis section has been translated automatically.
ManifestationThis section has been translated automatically.
The age of manifestation ranged from 4-86 years (median 49 years).
LocalizationThis section has been translated automatically.
In larger collectives (Hollmann 2012) 52% were located on the hands, 45% on the feet, and occasionally on the ankles and lower legs. > 95% of the neoplasms were sub- or periungual.
Clinical featuresThis section has been translated automatically.
Slowly growing over months or years, mostly periungual and leading to nail dystrophies, 0.5-5.0 cm in size (median 1.5 cm), often painful papules or nodules.
HistologyThis section has been translated automatically.
Unencapsulated myxoid neoplasm from spindle-shaped moderately nuclear and cellular polymorphs, CD34-positive fibroblasts, mixed with mast cells. Mitoses are missing. Sometimes also groups of multinuclear giant cells. Focal numerous blood vessels. Very rarely expression of alpha-smooth muscular actin and desmin. S-100 protein neg.
LiteratureThis section has been translated automatically.
- Carranza C et al (2015) Subungual Acral Fibromyxoma Involving the Bone: A Mimicker of Malignancy. At J Dermatopathol 37:555-559.
- Fetsch JF et al (2001) Superficial acral fibromyxoma: a clinicopathologic and immunohistochemical analysis of 37 cases of distinctive soft tissue tumor with a predilection for the fingers and toes. Hum Pathol 32: 704-714
- Hollmann TJ et al (2012) Digital fibromyxoma (superficial acral fibromyxoma): a detailed characterization of 124 cases. On J Surg Pathol 36:789-798.
- Moon A et al (2015) Myxoid dermatofibroma on a great toe: a case report. Int J Clin Exp Pathol 8:7605-7609.
- Sawaya JL et al (2015) Superficial acral fibromyxoma. Int J Dermatol. 54:499-508.
- Schwager ZA et al. (2015) Superficial acral fibromyxoma and other slow-growing tumors in acral areas. Cutis 95:E15-19.
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