Acne conglobata infantum L70.4

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Rare, but particularly severe form of acne infantum with nodules and abscessing fistula ducts. Endocrinological disorders frequent; clarification necessary!

Localization
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Confined to the face.

Clinical features
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papules, pustules, nodules and abscessed fistula ducts.

Laboratory
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Clarification: Total and free testosterone, dehydroepiandrosterone (DHEA and DHEA-S), LH, FSH.

Differential diagnosis
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Complication(s)
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Retracted fistulas.

External therapy
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Benzoyl peroxide (e.g. acne oxide) in lowest concentration, e.g. 1-2%, under observation for a few minutes, if necessary adapalene 0.1% (Differin gel/cream). Alternatively azelaic acid (e.g. Skinoren cream) can be tried. Deeply inflammatory efflorescences can be treated locally or intralesionally with glucocorticoids for a short time.

Internal therapy
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  • In the case of highly inflammatory components, antibiotics, especially erythromycin, e.g. paediathrocin 2 times/day 125 mg p.o., can be given systemically.
  • In pronounced, therapy-resistant cases, systemic treatment with isotretinoin should be considered in individual cases (0.36-1.0 mg/kg bw/day for 2-4 months). Cave! When treating with isotretinoin, no simultaneous administration of tetracyclines. Note the side effect profile of tetracyclines!

Progression/forecast
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Risk of considerable scarring, possibly continuation of the symptoms into adulthood.

Incoming links (1)

Acne infantum;

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Last updated on: 29.10.2020