Lactoferrin (inci)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Lactoferrin is a biological ingredient, an iron-binding glycoprotein from the transferrine family. Lactoferrin is synthesized in the human body by neutrophil granulocytes and by mucosal epithelial cells. The substance is found in high concentrations in colostrum and breast milk. In lower concentrations, lactoferrin is found in (exocrine) secretions such as tears, saliva, bile, pancreatic juice, urine, seminal fluid, vaginal mucus and phlegm of the nasal cavity, in lungs and in the gastrointestinal tract.

Field of application/use
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Lactoferrin is an important component of innate immunity. Lactoferrin has antimicrobial, immunomodulating, anti-inflammatory and antioxidant properties. The glycoprotein regulates the absorption and transport of iron. Lactoferrin is partially broken down by proteases in the stomach and small intestine. Peptides such as lactoferricin and lactoferrampin are formed, which also have a pronounced antimicrobial effect.

Cosmetics: Lactoferrin is used in cosmetic formulations. The lysate has a skin caring effect. It also acts as a hair conditioning agent (makes the hair easy to comb, smooth, soft and shiny and gives it volume).

Note(s)
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Lactoferrin was first detected in cow's milk (hence the name) and has the ability to bind free iron ions over a wide pH range.

Incoming links (1)

Oral streptococcae;

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Last updated on: 29.10.2020