Wine allergy Z88.9

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Wine allergy; Wine Allergy; Wine intolerance

Definition
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Wine allergies in the sense of a genuine type I or type IV allergy are extremely rare. The very rare IgE-mediated reactions, e.g. to the grapes themselves or to the noble rot fungus Botrytis cynerea, which do not play a major role in everyday allergy sufferers, come into consideration. Intolerance reactions after wine are frequent.

Occurrence/Epidemiology
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The occurrence of intolerance reactions is suspected in 0.2% of the population (data correspond to intolerance reactions in the French population).

Manifestation
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Women are more frequently affected than men

Clinical features
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These are pseudoallergic reactions to biogenic amines or to sulphites. Complaints include flushing (redness and hot flushes on the face, neck and décolleté), rhinitis, and more frequently headaches, breathing difficulties and/or circulatory problems.

Histamine intolerance is described as a non-immunological clinical symptomatology defined as an imbalance between histamine and the histamine-degrading enzyme diamine oxidase (DAO). This imbalance may be caused by a deficit in the activity of DAO or by an increased histamine intake through accumulated histamine (exogenous: e.g. through wine consumption).

Sulphites are mainly added to certain white wines and also cause pseudoallergic reactions depending on concentration. Sulphite is used for preservation. The declaration obligation only applies from 50 mg/kg, for wine from 400 mg/l.

Note(s)
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Sulphites are mainly added to certain white wines and also cause pseudoallergic reactions depending on concentration. Sulphite is used for preservation. The declaration obligation only applies from 50 mg/kg, for wine from 400 mg/l.

S.a. beer allergy

Literature
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  1. Borghesan: Allergy to wine. Allergy 59, 1135-1136 (2004)
  2. Kauffman HF et al (1987) Botrytis cinerea: a study of the immunological properties during growth. Incidence of antibodies against B.cinerea in a group of patients with aspergillosis. Int Arch Allergy Appl Immunol 83:359-365
  3. Popp W et al (1987) "Berry sorter's lung" or winegrower's lung--an exogenous allergic alveolitis caused by Botrytis cinereaspores. Clinic practice Pneumol 41:165-169
  4. Rainer-Längle C et al. (2015) Severe beer allergy of a brewery owner - High-grade instant type allergy to food and beer based on sensitization to non-specific lipid transfer proteins. JDDG 13 (Suppl 1): 112
  5. Wiegand P et al (2012) Prevalence of wine intoerance: results of a survey from Mainz, Germany. Dtsch Ärztebl Int 109: 4

Outgoing links (2)

Beer allergy; Intolerance reaction;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020