Lutein

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 07.01.2026

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Synonym(s)

CAS No. 127-40-2; Xanthophyll

Definition
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Lutein is a yellow carotenoid pigment that is widespread in nature. The term lutein is used synonymously with xanthophyll. The pigment is a companion of chlorophyll and is found in green plants, flowers, fruits, bacteria, egg yolks, cereal grains and as a dipalmitate in the retina of the eye.

Field of application/use
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food colouring (E 161 b), feed additive

Note(s)
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The term "xanthophylls" is used to describe (besides carotenes) a second group of carotenoids. Xanthophylls have a great chemical similarity to carotenes, but in contrast to them they contain oxygen-containing groups. Xanthophylls are differently coloured natural substances (in animals as well as in plants).

Literature
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  1. Manayi A et al(2015) Lutein and cataract: from bench to bedside. Crit Rev Biotechnol 36:829-839.
  2. Nataraj J et al (2016) Lutein protects dopaminergic neurons against MPTP-induced apoptotic death and motor dysfunction by amliorating mitochondrial disruption and oxidative stress. Nutr Neurosci 19:237-246.
  3. Roldán-Fidalgo A et al (2016) In vitro and in vivo effects of lutein against cisplatin-induced ototoxicity. Exp Toxicol Pathol 68:197-204.
  4. Tominari T et al (2017) Lutein, a carotenoid, suppresses osteoclastic bone resorption and stimulates bone formation in cultures. Biosci Biotechnol Biochem 81:302-306.
  5. Yoshizako H et al (2016) Comparison of macular pigment and serum lutein concentration changes between free lutein and lutein esters supplements in Japanese subjects. Acta Ophthalmol 94:e411-e416.

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Last updated on: 07.01.2026