Ficus benjamina

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Birch Fig; weeping fig

Definition
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Non-flowering, non-smelling green plant from the mulberry family (Moraceae) related to the rubber tree. In the open countryside, it grows up to 30 m in the area of origin and up to 3 m high as an indoor plant. Densely growing, dark green, oval to egg-shaped or eliptoid leaves.

Occurrence
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Originally based in India and other Asian countries. Widespread in Germany and other European countries as a popular houseplant.

Effects
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  • Highly potent "indoor allergen". Common trigger of allergic rhinitis, conjunctivitis and bronchial asthma (after inhalation of contaminated dust) up to lid oedema, contact urticaria, Quincke's oedema and shock symptoms. Trigger of a classical immediate type allergy with formation of specific IgE. Sensitizing potency: High!
  • Notice! Most of the sensitizations found are asymptomatic cases without clinical relevance. Clinically silent ficus benjamina sensitizations are regularly found in latex allergy sufferers.

  • Notice! As a relevant allergen it is ranked third behind house dust mites and animal epithelia.

Note(s)
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  • F. benjamina produces a milky latex juice that contains the allergens. At least 11 allergens have been identified so far. Three of these allergens (Fb-latex major allergens: 25 kDa, 28 kDa, 29 kDa) meet the criteria of a major allergen (50% of the blood samples of allergic persons tested react with these allergens). The allergenic proteins are released to the leaf surface and bind to dust particles and dust traps (e.g. carpets, rugs).
  • Cross-reactions of the F. benjamina allergens exist among others between F. benjamina and other ficus species, between ficus species and the fruits (figs) of the fig tree (Ficus caria) and between ficus allergens and natural latex (especially hevein).
  • Notice! Atopic persons with pre-existing sensitization to inhalation allergens and latex allergy sufferers should be advised against an attitude of F. benjamina.

Literature
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  1. Antico A et al (2003) Oral allergy syndrome to fig. Int Arch Allergy Immunol 131: 138-142
  2. Erdmann SM et al (2004) Sensitization to fig with cross-sensitization to weeping fig and natural rubber latex. Int Arch Allergy Immunol 133: 316
  3. Schenkelberger V, Friday M, Altmeyer P (1998) Ficus benjamina--the hidden allergen in the house. dermatologist 49: 2-5
  4. Werfel S et al (2001) Anaphylactic reaction to Ficus benjamina (weeping fig). dermatologist 52(10 Pt 2): 935-937

Incoming links (3)

Elisa; Latex allergy; Rubber allergy;

Outgoing links (1)

Latex allergy;

Authors

Last updated on: 29.10.2020