Antihistamines, topical

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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For the external therapy of pruritus, H 1 antagonists are used, for example: bamipine, chlorphenoxamine, clemastine, dimetinden, dioxopromethazine, diphenhydramine, levocabastine, triple amine.

Notice! The antipruriginous and antihistaminic effect of locally applied antihistamines has not been proven to date and is not without controversy regarding the risk of sensitization. Systemic administration is in any case preferable to topical application!

Indication
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Not undisputed: Pruritus due to slight skin affections like sunburn, insect bites or jellyfish erythema.

Limited indication
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Children < 2 years, weeping or bullous skin changes, application to the eye or mucous membranes.

Undesirable effects
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Risk of sensitization, agitation in small children, allergic skin reactions.

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Last updated on: 29.10.2020