Parahaemophilia D68.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

congenital factor V deficiency; Factor V deficiency congenital; Hypoproaczeleremia; Owen's disease

History
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Owren, 1947

Definition
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Autosomal recessive inherited factor V deficiency with a tendency to bleed.

Manifestation
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Early childhood.

Clinical features
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Bleeding of the nose, gums, ecchymosis, suffusions, menorrhages, gastrointestinal bleeding, cerebral bleeding, combination with other malformations possible.

Laboratory
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Extended prothrombin time.

Diagnosis
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Proof of factor V deficiency.

Therapy
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Fresh whole blood, fresh plasma.

Progression/forecast
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Awkward.

Literature
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  1. Owren P (1947) Parahaemophilia: haemorrhagic diathesis due to absence of a previously unknown clotting factor. Lancet I: 446-448

Outgoing links (1)

Ecchymoses;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020