Kallikrein-kinin-system

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Kallikreine is a group of proteolytic enzymes from which plasma kinines are derived. Five different types are distinguished, which represent a physiological regulatory system and control a number of physiological functions, e.g. in inflammation, vasodilatation, vasoconstriction, in post-capillary veins and in smooth muscle contraction. This system is activated by factor XIIa, releasing bradykinin, which activates t-PA.

Literature
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  1. HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 105.

Outgoing links (2)

Bradykinin; Factor xii;

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Last updated on: 29.10.2020