Fibrinolysis antagonists (overview)

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

The anticoagulant functions are opposed by antagonists that counteract them.

Antagonists of anticoagulation and their target molecules
Antagonists Target Molecules
alpha-2-antiplasmin plasmin, kallikrein, alpha-chymotrypsin, thrombin
PAI-1 t-PA, urokinase
PAI-2 Urokinase
PAI-3 (= PCa inhibitor) aPC
alpha-2-macroglobulin plasmin, aPC
Histidine-rich glycoprotein Fibrin, Fibrinogen
Thrombin-activated fibrinolysis inhibitor (TAFI) Plasmin

The anticoagulant functions are antagonized.

LiteratureThis section has been translated automatically.

  1. HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 111.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer