The alpha-2-macroglobulin is a coagulation inhibitor, which is present in the plasma in a concentration of 150-300mg/dl. Its molecular weight is 725,000 D. It is synthesized in the liver and has a half-life of about two to three days. Furthermore, the alpha-2-macroglobulin converts the complex of antithrombin III with the activated serine proteases into a stable compound and inhibits factor Xa. It does not competitively inactivate plasmin. It is located in the plasma and on the platelet membrane.
Alpha-2-macroglobulin
DefinitionThis section has been translated automatically.
General informationThis section has been translated automatically.
Standard value: The standard value is between 1.3 and 3.0 g/l in serum
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 113.