Doak

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Direct oral anticoagulants; NOAK; Non-vitamin K-dependent anticoagulants

Definition
This section has been translated automatically.

Direct oral anticoagulants, DOAK for short, is the generic term for a group of anticoagulant drugs that act directly against certain coagulation factors and can be taken orally. Since these substances have only been on the market for a few years, the term "new oral anticoagulants" or "non-vitamin K-dependent anticoagulants" NOAKs is used alternatively.

Pharmacodynamics (Effect)
This section has been translated automatically.

Anticoagulation by direct inhibition of factor Xa or thrombin. This results in a faster onset of action compared to vitamin K antagonists. There are currently 4 active ingredients available on the German market:

Details on the different active ingredients can be found under the respective keywords.

Incoming links (1)

Thrombin inhibitors direct;

Outgoing links (3)

Apixaban; Dabigatran; Rivaroxaban;

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Last updated on: 29.10.2020