Anistreplase
Synonym(s)
Acylated plasminogen streptokinase activator complex - APSAC
Definition
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Anistreplase is a fusion molecule of streptokinase and Lys-plasminogen. The fibrin binding capacity is higher than that of streptokinase and urokinase and therefore leads to an increased activation of plasminogen compared to these substances.
Half-life
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About 100 minutes.
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Dosage and method of use
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30 E over five minutes IV
Preparations
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Eminase®
Literature
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- HA Neumann (2014) The coagulation system. ABW-Scientific Publisher GmbH Berlin
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Prof. Dr. med. Peter Altmeyer