Cmax
Keywords
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Tmax; AUC;
Definition
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Cmax (maximum plasma concentration): In pharmacokinetics,Cmax refers to the highest concentration of a drug reached in blood plasma after its administration.
Pharmacokinetic significance:
-Cmax: The maximum measured plasma concentration of a drug (e.g., ng/ml).
-Tmax: The time at which Cmax is reached.
- AUC (Area Under the Curve): Area under the concentration-time curve; a measure of total systemic drug exposure.
-t½ ( elimination half-life): The time it takes for the plasma concentration to decrease by 50% during the terminal elimination phase.
