Vaginal microbiome

Lactobacilli, Döderlein rods, vaginal dysbiosis, vaginal flora, infertility, preterm birth; vaginal dysbiosis; vaginal microbiome.

The vaginalmicrobiome consists primarily of lactobacilli that produce lactic acid and hydrogen peroxide, particularly Döderlein rods. Dysbiosis leads to an overgrowth of pathogenic microorganisms; see also bacterial vaginosis. Premature births and reduced conception rates (up to and including infertility) have also been linked to a deficiency of lactobacilli. See also:urogenital microbiome.

In cases of dysbiosis, microbiological therapywith lactobacilli has shown good results. Lactobacillus gasseri and Lactobacillus rhamnosus are approved for use in Vagisan® Probio Flora vaginal capsules following antibiotic treatment for bacterial vaginosis.