Stramonii folium
Definition
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Dried leaves of the datura.
Quality specified in the European Pharmacopoeia (Ph. Eur.).
Phytopharmacologically, stramonium leaves may not be used due to the alkaloids they contain (hyoscyamine, scopolamine).
Quality is defined in the European Pharmacopoeia (Ph. Eur.).
HMPC: not processed - highly toxic due to alkaloid content
ESCOP: not processed - highly toxic due to alkaloid content
Commission E: negative monograph
Empirical medicine: asthma, spasmodic cough.
Stramonii semen: identical with Stramonii folium
Ingredients
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Strongly acting tropane alkaloids, especially L-hyoscyamine, scopolamine and atropine, withanolides, flavonoids and coumarins. The toxicity comes from the tropane alkaloids.
Undesirable effects
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5-60 minutes after ingestion: Atropine-like effects: mydriasis, dry mouth, anhidrosis, agitation, visual and auditory hallucinations, delirium, tachyarrhythmia, urinary retention, nausea, vomiting, constipation. Feeling of heat and flushing. Duration about 2 days.
see also atropine poisoning
Literature
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- https://arzneipflanzenlexikon.info/stechapfel.php
- https://www.awl.ch/heilpflanzen/datura_stramonium/stechapfel.htm
- Montag A (2023) Plants and skin. Springer-Verlag GmbH. S. 917-920