Quinic acid

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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acidum chinicum; CAS 77-95-2; quinic acid

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Quinic acid is widely used as a secondary plant substance in the plant world. So also in the bark of the quinic acid. Quinic acid was isolated from the cinchona bark in 1790. The organic acid forms small, easily water-soluble, slightly ethanol-soluble and ether-insoluble, acidic-tasting crystals.
The organic acid occurs both as free acid and esterified. Its ester compound with caffeic acid, the chlorogenic acid, can be detected in coffee.

Field of application/use
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Quinic acid is found in numerous fruits and tubers, such as: sugar beets, apricots, apples, blackberries, citrus fruits, blueberries, peaches, plums and coffee beans. Cynarin, a 1,5-di-O-caffeoyl-D-quinic acid is an artifact obtained during the aqueous extraction of artichoke leaves and has a cholesterol-lowering effect.

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In the human organism the absorbed quinic acid is reduced to benzoic acid and excreted as hippuric acid in the urine.
In earlier times against gout. Dos: 0,5g/p.o. several times a day.

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  1. Breda CA et al(2016) Phytochemical Analysis and Antifungal Activity of Extracts from Leaves and Fruit Residues of Brazilian Savanna Plants Aiming Its Use as Safe Fungicides. Nat Prod Bioprospect.6:195-204.
  2. Jiang XW et al (2016) Caffeoylquinic Acid Derivatives Protect SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide-Induced Injury Through Modulating Oxidative Status. Cell Mol Neurobiol. PubMed PMID: 27255971.

Incoming links (2)

Chinones; Chlorogenic acids (inci);

Outgoing links (2)

Artichoke; Cynarin;