Millefolii flos

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 11.04.2023

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Synonym(s)

achillea millifolium; Herba Millefolii; knight`s milfoil; militarily harsh; millefolii folia; soldier`s woundword; Yarrow herb

Definition
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Yarrow flowers, unlike Milefolii herba, the quality of Millefolii flos is not specified in the European Pharmacopoeia (Ph. Eur.).

HMPC monograph: Traditional-use: Internal: loss of appetite, mild cramp-like discomfort in the gastrointestinal tract, flatulence and bloating, mild menstrual cramps. External: small superficial wounds.
ESCOP monograph: Internal: loss of appetite, dyspeptic complaints, mild cramp-like complaints in the abdomen.; External: small wounds, mild skin and mucous membrane inflammations; sitz baths for painful cramping conditions in the female pelvis (pelvipathia vegetativa).
Commission E-monograph: Internal: loss of appetite, dyspeptic complaints, mild cramp-like complaints in the gastrointestinal tract; in the form of sitz baths for pelvipathia vegetativa).

Empirical medicine: Chronic inflammatory liver diseases, inflammation of the mucous membranes in the gastrointestinal tract, vulvitis, colpitis, inflammation of the skin and mucous membranes, in small wounds as a hemostyptic, externally in menstrual disorders.

Ingredients
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Efficacy determining ingredients are: Essential oil 0,1% - 1,0%, proazulene (including achillicin), sesquiterpene lactones as bitter substances, flavonoids (apigenin and luteolin) and flavonaglygics, phenolic carboxylic acids, tanning agents. The bitter value of the drug must be at least 3000 (DAB). After steam distillation up to 40% chamazulene is contained.

Effects
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Antioxidant, anti-edematous, antiseptic, antiphlogistic, choleretic, appetite stimulating.

Field of application/use
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Loss of appetite, dyspeptic complaints, painful cramps in the small pelvis. Superficial wounds.

Limited indication
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Hypersensitivity to other composites

Pregnancy/nursing period
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Not indicated due to lack of data

Dosage
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The daily dose is 4,0-4,5 g of yarrow herb when administered internally.
Preparations according to Commission E: Tea infusion (2-4g of yarrow herb) 2-4x/day.

Sitting baths: 100g of yarrow herb in 20L of water.

Undesirable effects
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Rarely contact allergies, itching, bruising, exanthema

Contraindication
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allergy to parts of plants, daisies, children under 12 years, external for skin infections

Trade names
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Cesrasanol®, Dr. Klinger's Bergischer Blutreinigungs- und Stoffwechseltee, Dr. Klinger's Herz- und Kreislauftee, Fugacid® Digestivum Tea, Fugacid® Uric Acid Tea, Gall-Liver Tea Cholaflux® vegetabile, Gall-Liver Tea Stada® N, Gerner Cholagogum N, Liver-Gall Tea, Stada® Stomach Tea

Literature
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  1. Aberer W (2008) Contact allergy and medicinal plants. JDDG 6:15-24
  2. Candan F et al. (2003) Antioxidant and antimicrobial activity of the essential oil and methanol extracts of Achillea millefolium subsp. millefolium Afan. (Asteraceae). J Ethnopharmacol 87: 215-220.
  3. Hausen BM, Vieluf K (1997) Allergy plants, plant allergens. Ecomed Verlag, Landsberg/Munich, pp. 85-87.
  4. Orth M et al. (2000) Enantiomeric monoterpenes in ether oil from Achillea millefolium s. I.--a taxonomically useful marker? Pharmacy 55: 456-459
  5. https://arzneipflanzenlexikon.info/schafgarbe.php
  6. https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-achillea-millefolium-l-flos_en.pdf
  7. Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 189-190