Liquiritin

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Definition
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Flavone glycoside which is detectable as an efficacy determining drug in the root of Glycyrrhiza glabra(Liquiritiae radix).

Spectrum of action
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Together with its aglycon Liquiritinigenin spasmolytic properties. Furthermore, neuroprotective, antibacterial and apoptosis-promoting properties have been demonstrated experimentally.

Literature
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  1. Jia SL et al (2016) Neuroprotective effects of liquiritin on cognitive deficits induced by soluble amyloid-β(1-42) oligomers injected into the hippocampus. J Asian Nat Prod Res 18:1186-1199.
  2. Kim SJ et al (2014) Enhanced skin delivery of liquiritigenin and liquiritin-loaded liposome-in-hydrogel complex system. Int J Cosmet Sci 36:553-560.
  3. Zhang W et al (2014) Effect of liquiritin on human intestinal bacteria growth: metabolism and modulation.
  4. Zhou Y et al (2014) Combination of liquiritin, isoliquiritin and isoliquirigenin induce apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells. Oncol Rep 31:298 304.

Incoming links (1)

Liquiritiae radix;

Outgoing links (3)

Aglycone; Flavonoids; Liquiritiae radix;