Convallariae majalis herba
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Definition
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Dried herb of the lily of the valley. The herb is poisonous, it contains cardiac steroids: cardenolides (cardenolide glycosides), especially convallatoxin, convalloside and convallotoxol.
HMPC: not processed
ESCOP: not edited
Commission E monograph (old: 1990): mild heart failure (NYHA stage II on exertion), old-age heart and chronic cor pulmonale, now obsolete, see below
Historically, folk medicine: cardiac insufficiency Now obsolete due to the limited therapeutic range (strong toxic effect of cardenolides!).
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Effects
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Positively inotropic, lowers increased left ventricular end-diastolic pressure, economizes cardiac work, lowers pathologically increased venous pressure, tonifies veins, diuretic effect, natriuretic and kaliuretic.
Undesirable effects
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Nausea, vomiting, diarrhea, cardiac arrhythmia
Contraindication
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Therapy with digitalis glycosides, potassium deficiency states
Interactions
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Enhancement of the effect of quinidine, calcium, saluretics, laxatives, glucocorticoids.
Literature
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- https://arzneipflanzenlexikon.info/maigloeckchen.php
Wenigmann M. (2017) Phytotherapy medicinal drugs, phytopharmaceuticals, application. Urban & Fischer, pp. 153-154