Berberidis radicis cortex

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 10.12.2025

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Synonym(s)

cortex berberidis radicis

Definition
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Berberidis radicis cortex is an extract from the root bark of the barberry (Berberis vulgaris).

Commission E: Negative monograph

ESCOP: not processed

HMPC: not processed

Cosmetic industry: Berberis vulgaris extract (INCI)

Ingredients
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The alkaloid berberine (1-3%), oxyacyanthine and its isomer berbamine. Also jatrorrhizin, columbamine, palmatine and various resins.

Spectrum of action
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The medical applications are not sufficiently proven. In folk medicine, the extracts are used as choloretics and cholecinetics in liver diseases. Applications are also known in homeopathy (stone formation, gout).

Undesirable effects
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Nausea, vomiting, diarrhea, kidney irritation, nephritis, respiratory paralysis.

Literature
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  1. Montag A (2023) Plants and skin. Springer-Verlag Ltd. S. 387-390
  2. https://www.awl.ch/heilpflanzen/berberis_vulgaris/berberitze.htm