Anti-ganglioside igg antibody

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Definition
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Gangliosides represent a structural family of glycosphingolipids. AK against gangliosides are detectable in 60% of patients with Guillain-Barré syndrome (GBS). They are found particularly in the acute phase and can therefore be used as disease markers.

The specificities are divided into 3 groups based on the epitope-providing gangliosides. Ant-gQ1bAK are specific for the Miller-Fisher syndrome, a variant of GBS.

General information
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Test material: Serum

Reference range: negative

Literature
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Manfras M et al (2018) Immunodiagnostics. In: Neumeister B et al. (Eds) Clinical guide to laboratory diagnostics. Elsevier GmbH S. 430