Ammeos visnagae fructus

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 25.01.2022

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Synonym(s)

Ammeifrüchte; Ammi-visnaga fruits; Khellafruits

Definition
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Ammeos visnagae fructus, also known as Ammi-visnaga fruits, is a drug used as a herbal medicine, among other things as an antispasmodic or diuretic for urinary and bladder problems and for coronary circulatory disorders.

Ingredients
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Effective ingredients of Ammi-visnaga fruits are Furanochrome: Khellin (up to 1 %), Khellosid, Visnadin, Khellol. Furthermore 0.2 and 0.5 % pyranocoumarin ester: e.g. visnadine, samidine, dihydrosamidine. Alkaloids: Khellinone and Visnaginone. In addition, the drug contains flavone glycosides, fatty oil, essential oils.

Field of application/use
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A negative monograph from Commission E is available on Ammi-visnaga fruit. However, the drug is used in various European countries.

The indications are mild stenocardial complaints and cramp-like abdominal complaints. Other indications include mild forms of obstructive respiratory symptoms, postoperative treatment of urinary stone disease, paroxymic tachycardia, and extrasystoles.

Dosage
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The usual average daily dose is 20 mg gamma-pyrone (calculated as khellin). The drug is administered in crushed form.

Undesirable effects
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The use of Ammi-visnaga fruits can lead to (pseudo-) allergies, reversible chronic icterus and sleep disorders. In addition, the skin is more sensitive to light due to the intake of khellin.

Note(s)
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During the use of Ammi-visnaga fruit, the patient should avoid uncontrolled sunbathing and UV radiation.

Literature
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  1. Schlicher H (2016) Leitfaden Phytotherapie, Urban & Fischer Verlag, Munich, p 51.