Sae antibodies

The SAE antibody (SAE stands for the acronym: small ubiquitin-like modifier activating enzyme) is found in about 5-8% of adult dermatomyositis. Typically, patients initially present with skin symptoms only and develop myositis later in the course of the disease. The SAE antibody is associated with a low incidence of malignancies or interstitial lung disease.

The SAE antibody (SAE stands for the acronym: small ubiquitin-like modifier activating enzyme) is found in about 5-8% of adult dermatomyositis. Typically, patients initially present with skin symptoms only and develop myositis later in the course of the disease. The SAE antibody is associated with a low incidence of malignancies or interstitial lung disease.

1. Volc-Place B (2015) Dermatomyositis update. Dermatologist 66:604-610