MSC Gene

Last updated on: 01.12.2021

Dieser Artikel auf Deutsch

Definition
This section has been translated automatically.

MSC (Musculin) is a protein coding gene located on chromosome 8q13.3. The protein encoded by this gene is a transcriptional repressor that can bind an E-box element in vitro either as a homodimer or as a heterodimer with E2A. This protein complex is capable of inhibiting the transactivation ability of E47, an E2A protein, in mammalian cells.

Note(s)
This section has been translated automatically.

Diseases associated with MSC include:

  • Alk-negative anaplastic large cell lymphoma

and

  • rhabdomyosarcoma.

Literature
This section has been translated automatically.

  1. Buchanan RM et al (2011) B-cell activating factor (BAFF) promotes CpG ODN-induced B cell activation and proliferation. Cell Immunol 271:16-28.
  2. Coffman RL et al (1986) B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J Immunol 136:4538-4541.

Incoming links (1)

PTCL;

Last updated on: 01.12.2021