Mollaret meningitis G03.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Benign recurrent meningitis; Recurrent aseptic meningitis

Definition
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Special form of the so-called "benign chronic recurrent meningitis" (Diaz-Hurtado M et al. 2006).

Etiopathogenesis
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Herpes simplex viruses (more frequently HSV 2) are probably the trigger of the disease.

Clinical features
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In general, the disease has a self-limiting course, although a recurrent course lasting several years is possible.

Diagnosis
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CSF typically contains pleocytosis with large endothelial cells (so-called mollaret cells), which are not pathognomic. HSV-2-PCR detection is occasionally successful.

Differential diagnosis
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Drug-induced aseptic meningitis (DIAM), which has identical symptoms and develops after administration of mainly NSAIDs (e.g. ibuprofen) and various antibiotics (Hopkins S et al. 2005)

Literature
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  1. Diaz-Hurtado M et al (2006) Vidal-Tolosa A. Drug-induced aseptic meningitis: A physician's challenge. J Natl Med Assoc 98: 457
  2. Hopkins S et al (2005) Drug-induced aseptic meningitis. Expert Opinion Drug Saf 4: 2985-2971

Outgoing links (1)

Herpes simplex virus;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020