LOF

Last updated on: 23.03.2024

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Definition
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Null mutation is a loss-of-function mutation (LOF) of a gene (null allele, also amorphous allele) in which there is a complete loss of function of the gene. Example: knock-out mice; if the function remains partially intact, this is referred to as hypomorphic.

Last updated on: 23.03.2024

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