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DefinitionThis section has been translated automatically.
Hub genes (node genes) are genes that play a central role in biological networks - especially in gene co-expression networks. The term was adopted from data network analysis in molecular biology. There, "hub" refers to a central node with a particularly large number of connections.
Hub genes are genes that interact or are co-expressed with many other genes. These genes are often regarded as central regulators because they can potentially influence many other genes.