Ft4

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Free Thyroxine

Definition
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Acroynm for free thyroxine (T4). Thyroid hormones are only biologically available and effective in free form. The majority of thyroid hormones are protein-bound. The advantage of the determination of free hormones is the independence of the binding capacity and concentration of the transport proteins (e.g. thyroxine-binding globulin).

General information
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test material: serum, plasma

Determination method: highly sensitive immunoassays

Reference values for fT4:

  • children (prepubertal): 10.3-28.3 pmol/l
  • Children (adolescent): 10,3-29,6 pmol/l
  • Adults: 10-23 pmol/l

Elevated values: manifest hyperthyroidism

Decreased values: manifest hypothyroidism

Literature
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  1. Böhm BO (2018) Thyroid hormones. In: Neumeister B et al. (Eds) Clinical guide to laboratory diagnostics.

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Last updated on: 29.10.2020