DefinitionThis section has been translated automatically.
DITRA is the acronym for: Interleukin-36 receptor antagonist deficiency syndrome. This is a rare autoinflammatory disorder caused by mutations in the IL36RN gene. This mutation leads to a lack of functional interleukin-36 receptor antagonists (IL-36Ra), resulting in an overactive immune system and chronic inflammation. For further details see below. Interleukin-36 receptor antagonist deficiency syndrome.
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