Cyanosis brown R23.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Brown cyanosis

Definition
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Brownish cyanosis in methemoglobinemia (iron in III-valent form). Triggered by therapy with sulfones/sulfonamides ( DADPS) or nitrites (nitrate-containing heart medication!), in case of G6PD deficiency, by nitrosegases, bitter almond products, hemoglobinopathies. In the laboratory, brown blood colour is impressive, which does not disappear when shaken. Met-Hb determination is positive. Heinz's inner body is found in the erythrocytes.

Therapy
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Administration of vitamin C: 500-1000 mg single dose, repeated if necessary. Alternatively: administration of methylene blue 2%, 10 ml i.v., repeat 1-2 times if necessary. Stop triggering medication, monitor the patient. Caution! Hemolysis! Hb control, if necessary substitution of erythrocyte concentrates.

Incoming links (1)

Cyanosis;

Outgoing links (2)

Cyanosis; Dadps;

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Last updated on: 29.10.2020