Constitutive

Last updated on: 25.11.2025

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Definition
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In a molecular biology context, "constitutive" means - permanently active - without regulator - independent of external stimuli.

General information
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Constitutive gene expression: A gene is permanently and uniformly expressed, regardless of the prevailing conditions. For example, genes for basic -conitutive- cell functions are referred to as "housekeeping genes".

Constitutive promoters: These are promoters that are always active and enable continuous transcription.

Constitutive enzymes/proteins: These are proteins that are permanently produced because they are indispensable for the cell.

Constitutively active receptors: Receptors that are active without ligand binding and constantly transmit a signal.

Last updated on: 25.11.2025