Caplan syndrome - Altmeyers Encyclopedia - Department Internal medicine

History
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Caplan 1953

Definition
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Combination of silicosis with rheumatoid arthritis. In contrast to pneumoconiosis, coarse-nodular lung changes develop relatively quickly, they occur singly or in multiples and have a diameter of 0.5-5.0 cm.

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Occurrence/Epidemiology
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Such changes are observed in 30% of patients with pneumoconiosis and chronic polyarthritis.

Histology
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Histologically there are no pneumoconiotic granulomas, but rheumatic nodules of the lung.

Literature
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Bloch KE et al (2017) Structural lung changes. In: Battegay E: Differential diagnosis of internal diseases. Georg Thieme Publisher Stuttgart, New York S 123-175