Acanthocyte

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Acanthocyte; Acanthocytes

Definition
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Pathological form of the erythrocytes. An acanthocyte has pointed spines ("sting cells") due to a disproportion between cell volume and cell membrane. The enlargement of the cell surface is caused by an increased absorption of cholesterol into the cell membrane. Acanthocytes are observed for example in some liver and blood diseases, after splenectomy and in some rare neurological diseases, the so-called neuro-acanthocytosis syndromes.

Note(s)
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Morphological differentiation from fragmentocytes and the so-called thorn-apple forms.

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Last updated on: 29.10.2020

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