Trichilemmal cyst proliferating D23.4

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Epithelioid cyst proliferating; Giant hair matrix tumor; Giant hair matrix tumor, tricholemic cyst proliferating; Pilar tumor of the scalp; Proliferating trichilemmal cyst; Proliferating trichilemmal tumor; Proliferating tricholemic cyst; Trichilemmal tumor proliferating

History
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Wilson-Jones, 1966

Definition
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Usually benign, pure follicularly differentiated adnexal tumor, which occurs predominantly on the hairy head and can assume clinically monstrous dimensions. It is not clear how a noslogical relationship to the trichilemmal cyst exists. Therefore, some authors prefer the term "proliferating trichilemmal tumor".

Manifestation
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Mostly occurring in older women (80-90% of cases).

Histology
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Multiple, differently sized cysts with mostly pseudoepitheliomatous hyperplasia of the cyst wall, abrupt trichilemmal keratinization; undifferentiated cell clusters are detectable in some tumors. In individual cases lymph node metastases have been detected (Rose C 2014).

Therapy
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Safe excision in healthy tissue with microscopically controlled surgery.

Progression/forecast
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Tendency to local recurrence. Infiltrative growth or metastasis are possible.

Literature
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  1. Burg G et al (1988) Proliferating tricholemmal tumor. dermatologist 39: 117-119
  2. Haas N et al (2002) Carcinoma arising in a proliferating trichilemmal cyst expresses fetal and trichilemmal hair phenotype. At J Dermatopathol 24: 340-344
  3. Hödl S et al (1984) On the dignity of the proliferating trichilemmal cyst. Dermatologist 35: 640-644
  4. Noto G et al (1997) Proliferating tricholemmal cyst should always be considered as a low-grade carcinoma. Dermatology 194: 374-375
  5. Rose C (2014) tumors of the scalp. Dermatologist 65: 1030-1036
  6. Van Zele D et al (2002) Invasive tricholemmal carcinoma of the nose. Dermatology 204: 315-317
  7. Jones EW (1966) Proliferating epidermoid cysts. Arch Dermatol 94: 11-19

Outgoing links (2)

Excision; Hyperplasia;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020