Toker cell

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Epithelial cells named after their discoverer Cyril Toker. Toker first described "clear cells" in the epidermis of the nipple in 1970. Toker cells are found physiologically in the epidermis of the nipple as well as in lower density in the epithelium of the vulva. Immunohistologically, they can be
representedby Toker cells with
antibodies for cytokeratin 7 and CEA. It is discussed that Paget's disease can be derived from Toker cells.

Literature
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  1. Willman JH et al (2005) Vulvar clear cells of Toker: precursors of extramammary Paget's disease. At J Dermatopathol 27:185-188.

Incoming links (1)

Paget's disease of the nipple;

Outgoing links (3)

Cea; Cytokeratin 7; Paget's disease;

Authors

Last updated on: 29.10.2020