Testosterone propionate
Synonym(s)
Hydrophilic testosterone propionate cream 2% (NRF 25.4.); Testosterone Ointment 2%
Definition
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Half-life
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20–48 h
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Indication
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Substitution therapy for hypogonadism and eunuchism, impotentia coeundi, locally for lichen sclerosus et atrophicus of men and women beyond menopause.
Dosage and method of use
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2-3 times/week 10-50 mg i.m.
Standard concentration
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2% in creams and ointments.
Undesirable effects
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Virilization (clitoral hypertrophy) in women, also with topical application.
Note(s)
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The local use of testosterone propionate has been common in lichen sclerosus et atrophicus for decades. However, there are considerable doubts about its effectiveness. Proof of effectiveness in controlled studies has never been provided.
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Prof. Dr. med. Peter Altmeyer