Smoker's leukoplakia K13.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Oral leukoplakia due to heavy smoking, e.g. on the lips of pipe smokers. Special form: Leukokeratosis nicotinica palati.

General therapy
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Stop smoking immediately and without fail, six-monthly check-ups to exclude malignancies.

Internal therapy
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Therapy trial with isotretinoin (e.g. isotretinoin-ratiopharm; acne normin) 0.2-0.5 mg/kg bw/day or acitretin (neotigason) in a medium dosage of 30 mg/day is possible.

Operative therapie
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Excision in healthy people is therapy of choice. If malignant changes are bioptically ruled out,CO2 laser therapy, cryosurgery (2 cycles in open spray procedure or as contact procedure) or soft X-ray therapy (30-50 Gy, fractionated in 5 Gy doses) can be considered alternatively.

Progression/forecast
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Transition to spinocellular carcinoma possible.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020